What Your Family Needs to Do in the First 48 Hours After Hospital Discharge

The moment the discharge paperwork is signed, most families exhale. The hospital stay is over. Your loved one is coming home. The crisis, it seems, has passed.

What most families don’t know, and what the research confirms, is that the first 48 to 72 hours after hospital discharge represent one of the highest-risk periods for older adults. Readmission rates within 30 days of discharge are significant for seniors. Most of those readmissions are preventable. And most of the prevention happens in the hours immediately following discharge, not in the weeks that follow.

Here is what your family actually needs to do.

Most families don’t know this person exists. Every hospital has discharge planners or medical social workers whose job is to connect patients and families with the support they need to transition home safely. Ask for them by name. Ask to meet with them before discharge day, not on discharge day.

A good discharge planner can help you understand what care is covered by insurance, what resources are available in your community, and what level of support your loved one is likely to need in the days and weeks ahead. They can also make referrals to home care agencies and coordinate equipment orders. Do not leave the hospital without having had this conversation.

Before your loved one leaves, confirm you have the complete discharge paperwork. This should include a full current medication list with dosages and timing, a summary of the diagnoses and procedures, clear instructions for wound care or other follow-up tasks, a list of all scheduled follow-up appointments, and any equipment orders such as a walker, wheelchair, or oxygen.

Read through the paperwork before leaving. Ask questions about anything unclear. The discharge summary is your reference document for the days ahead; it needs to be complete and understood.

Do not wait until after discharge to begin arranging home care support. If your loved one is going to need help at home, start making calls while they are still in the hospital. Most reputable home care agencies can begin services within 24 to 48 hours of an initial request, but only if the request is made in time. Waiting until discharge day leaves very little room to arrange the right support.

If the need is urgent, say so directly when you call. Agencies can prioritize intake accordingly.

The first 24 hours after discharge require a real, physical presence at home. Not a family member who is available by phone or can be there in 20 minutes. Someone present in the home. Older adults who have just been discharged from the hospital are at elevated risk for falls, medication errors, and medical complications in the immediate hours following discharge. The presence of another person is the most effective safeguard available.

One of the most common causes of preventable readmission is medication error following discharge. This can mean taking old medications alongside new ones, missing critical doses, or misunderstanding the timing of a new regimen.

Sit down with the new medication list and go through it systematically. Identify every medication your loved one was taking before the hospital stay. Identify every new medication prescribed at discharge. Flag any duplicates, interactions you are uncertain about, or instructions that are unclear. If you have any concerns, call the discharging physician’s office or the pharmacist. Pharmacists are frequently the most accessible and underused resource in this process.

If possible, do a walkthrough of the home before your loved one returns from the hospital. Identify fall hazards: loose rugs, cords across walkways, poor lighting in bathrooms and stairwells. Assess whether the bathroom has appropriate safety features for the current situation. Move items your loved one will need, medications, phone, TV remote, and frequently used items, to within easy reach so they do not have to navigate the home unnecessarily in the first hours.

Review the discharge paperwork and confirm all follow-up appointments are in the calendar with dates, times, and addresses. Confirm how your loved one will get to each appointment. Many families overlook this step and discover at 8 am on appointment day that transportation has not been arranged.

The following signs in the first 72 hours after discharge should be treated as reasons to call the discharging physician or, if necessary, to seek emergency evaluation:

  • Fever, chills, or signs of infection at any wound or procedure site
  • Significant new confusion or disorientation that was not present at discharge
  • Worsening shortness of breath, chest pain, or other cardiovascular symptoms
  • Inability to keep medications or fluids down
  • A fall
  • Sudden change in level of alertness or responsiveness

If you are uncertain whether something warrants a call, call anyway. The discharging physician expects to hear from families in the days following discharge. That is what they are there for.

Research consistently shows that professional home care support in the days following hospital discharge significantly reduces readmission risk. The mechanism is straightforward: trained caregivers notice changes in condition, ensure medication adherence, support safe mobility, and provide the consistent monitoring that family members cannot always maintain around the clock.

Even temporary home care, arranged for the first week or two of recovery, can make a meaningful difference in outcomes. If your loved one was managing well before the hospitalization, a short-term engagement with a home care agency during recovery may be all that is needed. A care assessment during that time can also help determine whether longer-term support makes sense.

  • How do we set up home care quickly after a hospital discharge?
  • What is included in a home care plan?
  • What is the difference between home care and home health care?

  1. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among Patients in the Medicare Fee-for-Service Program. New England Journal of Medicine. 2009;360:1418-1428. https://www.nejm.org
  2. Agency for Healthcare Research and Quality (AHRQ). Re-Engineered Discharge (RED) Toolkit. Updated 2023. https://www.ahrq.gov/patient-safety/settings/hospital/red/index.html
  3. Centers for Medicare & Medicaid Services (CMS). Home Health Quality Reporting Program. Updated 2024. https://www.cms.gov/Medicare/Quality-Initiatives-Patient-Assessment-Instruments/HomeHealthQualityInits
  4. National Transitions of Care Coalition. Improving Transitions of Care: The Vision of the National Transitions of Care Coalition. 2022. https://www.ntocc.org

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